Transcatheter aortic valve replacement: current state of development

Transcatheter aortic valve replacement is a transformative technology for the treatment of severe aortic stenosis. It has allowed for the treatment of high-risk and inoperable aortic stenosis patients that would previously have not been able to undergo surgical aortic valve replacement. The safety and efficacy of transcatheter aortic valve replacement has been evaluated rigorously in multiple pivotal randomized clinical trials. Advancements in the technology with significant improvement in clinical outcomes and safety of the procedure have allowed for the extension to lower-risk groups. Future development will focus on continued refinement in the device and technique with expansion to low-risk patients and other clinical indications.