Stenotrophomonas skull base osteomyelitis presenting as necrotizing otitis externa: Unmasking by CT and MRI—case report and review

Necrotizing or malignant otitis externa in patients presenting with mild clinical findings can pose as a tip of the iceberg; computed tomography (CT) and/or magnetic resonance imaging (MRI) unveils the clinical-imaging discrepancy and unmasks the presence of skull-base osteomyelitis (SBO). Pseudomonas aeruginosa is the most common causative pathogen of SBO, followed by fungal and other rare bacterial organisms. This report presents a rare case in an elderly diabetic patient, where the pathogen Stenotrophomonas maltophilia was isolated. There have been no previous reported cases in the literature of SBO caused by this pathogen. The hallmark of SBO on computed tomography or magnetic resonance imaging is soft tissue inflammatory changes under the central skull base with associated bone erosion. This may result in the peculiar appearance of the “Ovoid Gap” sign. SBO can be due to nonotogenic sources, namely: sinogenic, rhinogenic, pharnygogenic, or odontogenic infections. Low threshold for imaging is advised in immunosuppressed and elderly diabetic patients.