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Proteomic approaches in the study of cancers

  • Khair Ul Nisa
  • , Najeebul Tarfeen
  • , Humaira
  • , Saba Wani
  • , Qadrul Nisa
  • , Shafat Ali
  • , Adil Farooq Wali
  • University of Kashmir
  • Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Proteomic tools have revolutionized the modern molecular sciences and have gained a special position in the field of cancer research. Advanced proteomic tools have identified several novel proteins and peptides and unraveled their basic pathways leading to cancer growth and metastasis. The success of treating cancers directly depends on how early they are detected. Proteomics have allowed researchers to identify and characterize novel predictive biomarkers that occur in the early phases of tumorigenesis, thus presenting valuable source for cancer therapeutic targets. Importantly, the integration of proteomics studies with other omics is providing extensive data related to molecular mechanisms and target modulators. In this chapter, we aim to provide an overview of cancer proteomics and recent advances made in the proteomic tools that have paved way to discover new therapeutic targets in various carcinomas.

Original languageEnglish
Title of host publicationProteomics
Subtitle of host publicationA Promising Approach for Cancer Research
PublisherElsevier
Pages205-217
Number of pages13
ISBN (Electronic)9780323950725
ISBN (Print)9780323950732
DOIs
StatePublished - 1 Jan 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Biomarkers
  • Cancer
  • Metastasis
  • Proteomics
  • Therapeutics

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