Proanthocyanidins: A comprehensive review

Abdur Rauf; Muhammad Imran; Tareq Abu-Izneid; Iahtisham-Ul-Haq; Seema Patel; Xiandao Pan; Saima Naz; Ana Sanches Silva; Farhan Saeed; Hafiz Ansar Rasul Suleria

doi:10.1016/j.biopha.2019.108999

Proanthocyanidins: A comprehensive review

Abdur Rauf
, Muhammad Imran
, Tareq Abu-Izneid
, Iahtisham-Ul-Haq
, Seema Patel
, Xiandao Pan
, Saima Naz
, Ana Sanches Silva
, Farhan Saeed
, Hafiz Ansar Rasul Suleria

Al Ain University of Science and Technology

University of Swabi
The University of Lahore
Imperial College London
San Diego State University
Chinese Academy of Medical Sciences
Women University Mardan
INIAV- Instituto Nacional de Investigação Agrária e Veterinária, IP, Quinta do Marquês
Government College University Faisalabad
University of Melbourne

Research output: Contribution to journal › Review article › peer-review

752 Scopus citations

Abstract

Proanthocyanidins are condensed tannins with various pharmacological properties. These phytochemicals are considered as ‘offense and defense molecules because of their human health benefits. The validation of their diverse health aspects, namely, antioxidant, anticancer, antidiabetic, neuroprotective, and antimicrobial has earned them repute in thermochemistry. Proanthocyanidins are oligo- or polymers of monomeric flavan-3-ols produced as an end product of flavonoid biosynthetic pathway. Agricultural wastes and food processing wastes contain immense amount of proanthocyanidins, exploitation of which can be a sustainable source of dietary supplements and functional ingredients. The current review article discusses recent developments in the health promoting properties of proanthocyanidins and the associated hurdles.

Original language	English
Article number	108999
Journal	Biomedicine and Pharmacotherapy
Volume	116
DOIs	https://doi.org/10.1016/j.biopha.2019.108999
State	Published - Aug 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 12 Responsible Consumption and Production

Keywords

Anticancer
Antidiabetic
Antioxidant capacity
Bio-active compound
Cardiovascular disease
Condensed tannin

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10.1016/j.biopha.2019.108999

Cite this

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title = "Proanthocyanidins: A comprehensive review",

abstract = "Proanthocyanidins are condensed tannins with various pharmacological properties. These phytochemicals are considered as {\textquoteleft}offense and defense molecules because of their human health benefits. The validation of their diverse health aspects, namely, antioxidant, anticancer, antidiabetic, neuroprotective, and antimicrobial has earned them repute in thermochemistry. Proanthocyanidins are oligo- or polymers of monomeric flavan-3-ols produced as an end product of flavonoid biosynthetic pathway. Agricultural wastes and food processing wastes contain immense amount of proanthocyanidins, exploitation of which can be a sustainable source of dietary supplements and functional ingredients. The current review article discusses recent developments in the health promoting properties of proanthocyanidins and the associated hurdles.",

keywords = "Anticancer, Antidiabetic, Antioxidant capacity, Bio-active compound, Cardiovascular disease, Condensed tannin",

author = "Abdur Rauf and Muhammad Imran and Tareq Abu-Izneid and Iahtisham-Ul-Haq and Seema Patel and Xiandao Pan and Saima Naz and \{Sanches Silva\}, Ana and Farhan Saeed and \{Rasul Suleria\}, \{Hafiz Ansar\}",

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year = "2019",

month = aug,

doi = "10.1016/j.biopha.2019.108999",

language = "English",

volume = "116",

journal = "Biomedicine and Pharmacotherapy",

issn = "0753-3322",

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T2 - A comprehensive review

AU - Rauf, Abdur

AU - Imran, Muhammad

AU - Abu-Izneid, Tareq

AU - Iahtisham-Ul-Haq,

AU - Patel, Seema

AU - Pan, Xiandao

AU - Naz, Saima

AU - Sanches Silva, Ana

AU - Saeed, Farhan

AU - Rasul Suleria, Hafiz Ansar

PY - 2019/8

Y1 - 2019/8

N2 - Proanthocyanidins are condensed tannins with various pharmacological properties. These phytochemicals are considered as ‘offense and defense molecules because of their human health benefits. The validation of their diverse health aspects, namely, antioxidant, anticancer, antidiabetic, neuroprotective, and antimicrobial has earned them repute in thermochemistry. Proanthocyanidins are oligo- or polymers of monomeric flavan-3-ols produced as an end product of flavonoid biosynthetic pathway. Agricultural wastes and food processing wastes contain immense amount of proanthocyanidins, exploitation of which can be a sustainable source of dietary supplements and functional ingredients. The current review article discusses recent developments in the health promoting properties of proanthocyanidins and the associated hurdles.

AB - Proanthocyanidins are condensed tannins with various pharmacological properties. These phytochemicals are considered as ‘offense and defense molecules because of their human health benefits. The validation of their diverse health aspects, namely, antioxidant, anticancer, antidiabetic, neuroprotective, and antimicrobial has earned them repute in thermochemistry. Proanthocyanidins are oligo- or polymers of monomeric flavan-3-ols produced as an end product of flavonoid biosynthetic pathway. Agricultural wastes and food processing wastes contain immense amount of proanthocyanidins, exploitation of which can be a sustainable source of dietary supplements and functional ingredients. The current review article discusses recent developments in the health promoting properties of proanthocyanidins and the associated hurdles.

KW - Anticancer

KW - Antidiabetic

KW - Antioxidant capacity

KW - Bio-active compound

KW - Cardiovascular disease

KW - Condensed tannin

UR - https://www.scopus.com/pages/publications/85066149509

U2 - 10.1016/j.biopha.2019.108999

DO - 10.1016/j.biopha.2019.108999

M3 - Review article

C2 - 31146109

AN - SCOPUS:85066149509

SN - 0753-3322

VL - 116

JO - Biomedicine and Pharmacotherapy

JF - Biomedicine and Pharmacotherapy

M1 - 108999

ER -

Proanthocyanidins: A comprehensive review

Abstract

UN SDGs

Keywords

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