TY - JOUR
T1 - Mortality and disability-adjusted life years in North Africa and Middle East attributed to kidney dysfunction
T2 - a systematic analysis for the Global Burden of Disease Study 2019
AU - GBD 2019 NAME Kidney Dysfunction Risk Factor Collaborators
AU - Rashidi, Mohammad Mahdi
AU - Moghaddam, Sahar Saeedi
AU - Azadnajafabad, Sina
AU - Mohammadi, Esmaeil
AU - Khalaji, Amirmohammad
AU - Malekpour, Mohammad Reza
AU - Keykhaei, Mohammad
AU - Rezaei, Negar
AU - Esfahani, Zahra
AU - Rezaei, Nazila
AU - Mokdad, Ali H.
AU - Murray, Christopher J.L.
AU - Naghavi, Mohsen
AU - Larijani, Bagher
AU - Farzadfar, Farshad
AU - Abbasi-Kangevari, Mohsen
AU - Abbasi-Kangevari, Zeinab
AU - ElHafeez, Samar Abd
AU - Abd-Elsalam, Sherief
AU - Abdoun, Meriem
AU - Abu-Gharbieh, Eman
AU - Ahmad, Aqeel
AU - Ahmed, Ayman
AU - Al-Azzam, Sayer
AU - Al-Raddadi, Rajaa M.
AU - AlTammemi, Ala'a B.
AU - Dehkordi, Javad Aminian
AU - Behghadami, Mehrdad Amir
AU - Arabloo, Jalal
AU - Athar, Mohammad
AU - Athari, Seyyed Shamsadin
AU - Babaei, Mahsa
AU - Babamohamadi, Hassan
AU - Baghcheghi, Nayereh
AU - Bagherieh, Sara
AU - Baradaran, Hamid Reza
AU - Bhagavathula, Akshaya Srikanth
AU - Bhojaraja, Vijayalakshmi S.
AU - Hashemi, Milad Bonakdar
AU - Campos, Luciana Aparecida
AU - Dehghan, Azizallah
AU - Elhadi, Muhammed
AU - El-Huneidi, Waseem
AU - Fatehizadeh, Ali
AU - Feizkhah, Alireza
AU - Ghadirian, Fataneh
AU - Gholami, Ali
AU - Hamidi, Samer
AU - Khan, Moien A.B.
AU - Sharif-Askari, Fatemeh Saheb
N1 - Publisher Copyright:
© The Author(s) 2023. Published by Oxford University Press on behalf of the ERA. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
PY - 2024/1/1
Y1 - 2024/1/1
N2 - Background. The study aimed to estimate the attributable burden to kidney dysfunction as a metabolic risk factor in the North Africa and Middle East (NAME) region and its 21 countries in 1990-2019. Methods. The data used in this study were obtained from the Global Burden of Diseases (GBD) 2019 study, which provided estimated measures of deaths, disability-adjusted life years (DALYs), and other epidemiological indicators of burden. To provide a better insight into the differences in the level of social, cultural, and economic factors, the Socio-Demographic Index (SDI) was used. Results. In the NAME region in 2019, the number of deaths attributed to kidney dysfunction was 296 632 (95% uncertainty interval: 249 965-343 962), which was about 2.5 times higher than in the year 1990. Afghanistan, Egypt, and Saudi Arabia had the highest, and Kuwait, Turkey, and Iran (Islamic Republic of) had the lowest age-standardized rate of DALYs attributed to kidney dysfunction in the region in 2019. Kidney dysfunction was accounted as a risk factor for ischemic heart disease, chronic kidney disease, stroke, and peripheral artery disease with 150 471, 111 812, 34 068, and 281 attributable deaths, respectively, in 2019 in the region. In 2019, both low-SDI and high-SDI countries in the region experienced higher burdens associated with kidney dysfunction compared to other countries. Conclusions. Kidney dysfunction increases the risk of cardiovascular diseases burden and accounted for more deaths attributable to cardiovascular diseases than chronic kidney disease in the region in 2019. Hence, policymakers in the NAME region should prioritize kidney disease prevention and control, recognizing that neglecting its impact on other diseases is a key limitation in its management.
AB - Background. The study aimed to estimate the attributable burden to kidney dysfunction as a metabolic risk factor in the North Africa and Middle East (NAME) region and its 21 countries in 1990-2019. Methods. The data used in this study were obtained from the Global Burden of Diseases (GBD) 2019 study, which provided estimated measures of deaths, disability-adjusted life years (DALYs), and other epidemiological indicators of burden. To provide a better insight into the differences in the level of social, cultural, and economic factors, the Socio-Demographic Index (SDI) was used. Results. In the NAME region in 2019, the number of deaths attributed to kidney dysfunction was 296 632 (95% uncertainty interval: 249 965-343 962), which was about 2.5 times higher than in the year 1990. Afghanistan, Egypt, and Saudi Arabia had the highest, and Kuwait, Turkey, and Iran (Islamic Republic of) had the lowest age-standardized rate of DALYs attributed to kidney dysfunction in the region in 2019. Kidney dysfunction was accounted as a risk factor for ischemic heart disease, chronic kidney disease, stroke, and peripheral artery disease with 150 471, 111 812, 34 068, and 281 attributable deaths, respectively, in 2019 in the region. In 2019, both low-SDI and high-SDI countries in the region experienced higher burdens associated with kidney dysfunction compared to other countries. Conclusions. Kidney dysfunction increases the risk of cardiovascular diseases burden and accounted for more deaths attributable to cardiovascular diseases than chronic kidney disease in the region in 2019. Hence, policymakers in the NAME region should prioritize kidney disease prevention and control, recognizing that neglecting its impact on other diseases is a key limitation in its management.
KW - cardiovascular diseases
KW - chronic kidney disease
KW - global burden of disease
KW - kidney dysfunction
KW - mortality
UR - https://www.scopus.com/pages/publications/85184021750
U2 - 10.1093/ckj/sfad279
DO - 10.1093/ckj/sfad279
M3 - Article
AN - SCOPUS:85184021750
SN - 2048-8505
VL - 17
JO - Clinical Kidney Journal
JF - Clinical Kidney Journal
IS - 1
M1 - sfad279
ER -
SDG 3 Good Health and Well-being