Intraoperative Evaluation of Surgical Margins in Breast-Conserving Therapy

Stephanie A. Valente; Stephen R. Grobmyer

doi:10.1016/B978-0-323-83365-3.00032-7

Intraoperative Evaluation of Surgical Margins in Breast-Conserving Therapy

Stephanie A. Valente
, Stephen R. Grobmyer

Cleveland Clinic Abu Dhabi

Cleveland Clinic Foundation
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Breast-conserving surgery is the preferred treatment approach for most patients with early-stage breast cancer. The goal is to achieve clear surgical margins at the time of lumpectomy, for which national guidelines recommend no ink on tumor for invasive disease and 2-mm margins for ductal carcinoma in situ. Traditional intraoperative margin assessment techniques include frozen section, cytology, intraoperative ultrasound, and specimen radiography. This chapter reviews data regarding the prognostic significance of margin status, describes the techniques currently used for the intraoperative evaluation of margins and compares the relative benefits and limitations of each approach..

Original language	English
Title of host publication	Bland and Copeland's The Breast
Subtitle of host publication	Comprehensive Management of Benign and Malignant Diseases
Publisher	Elsevier
Pages	404,407.e1-407,407.e1
ISBN (Electronic)	9780323833653
ISBN (Print)	9780323833660
DOIs	https://doi.org/10.1016/B978-0-323-83365-3.00032-7
State	Published - 1 Jan 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

breast-conserving surgery
cytology
frozen section
intraoperative assessment
lumpectomy
margins
partial mastectomy
shave margins
specimen radiograph
touch prep
ultrasound

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10.1016/B978-0-323-83365-3.00032-7

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abstract = "Breast-conserving surgery is the preferred treatment approach for most patients with early-stage breast cancer. The goal is to achieve clear surgical margins at the time of lumpectomy, for which national guidelines recommend no ink on tumor for invasive disease and 2-mm margins for ductal carcinoma in situ. Traditional intraoperative margin assessment techniques include frozen section, cytology, intraoperative ultrasound, and specimen radiography. This chapter reviews data regarding the prognostic significance of margin status, describes the techniques currently used for the intraoperative evaluation of margins and compares the relative benefits and limitations of each approach..",

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AB - Breast-conserving surgery is the preferred treatment approach for most patients with early-stage breast cancer. The goal is to achieve clear surgical margins at the time of lumpectomy, for which national guidelines recommend no ink on tumor for invasive disease and 2-mm margins for ductal carcinoma in situ. Traditional intraoperative margin assessment techniques include frozen section, cytology, intraoperative ultrasound, and specimen radiography. This chapter reviews data regarding the prognostic significance of margin status, describes the techniques currently used for the intraoperative evaluation of margins and compares the relative benefits and limitations of each approach..

KW - breast-conserving surgery

KW - cytology

KW - frozen section

KW - intraoperative assessment

KW - lumpectomy

KW - margins

KW - partial mastectomy

KW - shave margins

KW - specimen radiograph

KW - touch prep

KW - ultrasound

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M3 - Chapter

AN - SCOPUS:105021618663

SN - 9780323833660

SP - 404,407.e1-407,407.e1

BT - Bland and Copeland's The Breast

PB - Elsevier

ER -

Intraoperative Evaluation of Surgical Margins in Breast-Conserving Therapy

Abstract

UN SDGs

Keywords

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