TY - JOUR
T1 - International consensus recommendations for the RAPID procedure in liver transplantation
AU - The RAPID Consensus ISLS 2023 Zurich Collaborative
AU - Malagó, Massimo
AU - Line, Pål Dag
AU - Balci, Deniz
AU - Raptis, Dimitri
AU - Nadalin, Silvio
AU - Scatton, Olivier
AU - Bhangui, Prashant
AU - Settmacher, Utz
AU - Quintini, Cristiano
AU - Troisi, Roberto
AU - Soejima, Yuji
AU - Lerut, Jan
AU - Saiura, Akio
AU - Mayr, Andreas
AU - Alkheraiji, Badriah Salem
AU - Kabaçam, Gökhan
AU - Spiro, Michael
AU - Selzner, Nazia
AU - Ergonul, Onder
AU - Ottesen, Øyvind Heen
AU - Fritsch, Ralph
AU - Shrikhande, Shailesh
AU - Salinas, Camila Hidalgo
AU - Zachiotis, Marinos
AU - Machairas, Nikolaos
AU - Tinguely, Pascale
AU - Bousi, Stelios Elion
AU - Ekser, Burcin
AU - Azoulay, Daniel
AU - Fernandes, Eduardo
AU - Lim, Chetana
AU - Halazun, Karim
AU - Kim, Ki Hun
AU - Golse, Nicolas
AU - Brustia, Raffaele
AU - Humar, Abhinav
AU - Kim, Dong Sik
AU - Adali, Gupse
AU - Fronek, Jiri
AU - Yagi, Shintaro
AU - Rauchfuß, Falk
AU - Dondossola, Daniele
AU - Sturdevant, Mark
AU - Barriga, Mauricio Sainz
AU - Uso, Teresa Diago
AU - Chan, Albert
AU - Panaro, Fabrizio
AU - Rompianesi, Gianluca
AU - Kow, Alfred
AU - Hashimoto, Koji
N1 - Publisher Copyright:
© 2025 The Author(s).
PY - 2025/4/1
Y1 - 2025/4/1
N2 - Introduction: Since its beginning in 1963, liver transplantation has significantly advanced, now including transplant oncology. As indications broaden, donor supply reduces. The two-stage RAPID procedure (initially abbreviated as “Resection And Partial Liver Segment 2/3 Transplantation With Delayed Total Hepatectomy”) has emerged to address the use of small-for-size grafts. However, a comprehensive evaluation of RAPID is essential given its novelty, scarcity, and diverse outcomes reported. Methods: The RAPID Consensus International Society of Liver Surgeons 2023 Zurich initiative established evidence around the RAPID procedure using the Danish Model of Consensus. Engaging an international community of specialists, the initiative ensured multidisciplinary involvement and used the GRADE framework to evaluate the quality of evidence and grade the recommendations. Results: Comprehensive discussions and debates led to internationally recognized recommendations addressing perioperative measures for RAPID. Key recommendations highlighted the significance of standardized nomenclature, specific indications, graft criteria, surgical techniques, optimal interstage timings, and measures to manage potential complications. Conclusion: The consensus provides recommendations for the RAPID procedure, emphasizing transparency and outcome reporting. Establishing dedicated registries can improve care standards, which may ensure the benefits of RAPID by maximizing patient safety and improving outcomes.
AB - Introduction: Since its beginning in 1963, liver transplantation has significantly advanced, now including transplant oncology. As indications broaden, donor supply reduces. The two-stage RAPID procedure (initially abbreviated as “Resection And Partial Liver Segment 2/3 Transplantation With Delayed Total Hepatectomy”) has emerged to address the use of small-for-size grafts. However, a comprehensive evaluation of RAPID is essential given its novelty, scarcity, and diverse outcomes reported. Methods: The RAPID Consensus International Society of Liver Surgeons 2023 Zurich initiative established evidence around the RAPID procedure using the Danish Model of Consensus. Engaging an international community of specialists, the initiative ensured multidisciplinary involvement and used the GRADE framework to evaluate the quality of evidence and grade the recommendations. Results: Comprehensive discussions and debates led to internationally recognized recommendations addressing perioperative measures for RAPID. Key recommendations highlighted the significance of standardized nomenclature, specific indications, graft criteria, surgical techniques, optimal interstage timings, and measures to manage potential complications. Conclusion: The consensus provides recommendations for the RAPID procedure, emphasizing transparency and outcome reporting. Establishing dedicated registries can improve care standards, which may ensure the benefits of RAPID by maximizing patient safety and improving outcomes.
KW - Danish model of consensus
KW - GRADE framework
KW - RAPID
KW - international recommendations
KW - liver transplantation
KW - transplant oncology
UR - https://www.scopus.com/pages/publications/105003783991
U2 - 10.1097/JS9.0000000000002145
DO - 10.1097/JS9.0000000000002145
M3 - Article
C2 - 39907624
AN - SCOPUS:105003783991
SN - 1743-9191
VL - 111
SP - 2766
EP - 2772
JO - International Journal of Surgery
JF - International Journal of Surgery
IS - 4
ER -