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Comparison of Machine Learning Algorithms for classification of Late Onset Alzheimer's disease

  • Abbas Saad Alatrany
  • , Abir Hussain
  • , Saad S.J. Alatrany
  • , Jamila Mustafina
  • , Dhiya Al-Jumeily
  • Liverpool John Moores University
  • University of Information Technology and Communications
  • Imam Ja'afar Al-Sadiq University
  • Kazan Volga Region Federal University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

12 Scopus citations

Abstract

Alzheimer's disease (AD) is neurodegenerative brain illness. It is classified as a degenerative illness since it worsens with time. A multitude of risk factors contribute to the development of Alzheimer's disease, such as demographic information, test scores, and genetics. The paper presents the comparison of machine learning algorithms to identify the highest accuracy level in classification of Late Onset Alzheimer's disease. Dataset from the Alzheimer's Disease Neuroimaging Initiative has been requested to train and test the machine learning models. The dataset included 539 normal controls and 411 Alzheimer's Disease individuals. A main dataset includes variables that are often used in clinical practice to develop the machine learning algorithms. Another dataset was created that exclusively included subjects aged 65 and up in order to assess the accuracy of algorithms used to diagnose late-onset Alzheimer's disease. According to the benchmarked findings, Linear Discriminant Analysis performed the most efficiently, achieving accuracy and an F1-score of 1.

Original languageEnglish
Title of host publicationDeSE 2023 - Proceedings
Subtitle of host publication15th International Conference on Developments in eSystems Engineering
EditorsDhiya Al-Jumeily, Header Abed Dhahad, Manj Jayabalan, Jade Hind, Jamila Mustafina, Sulaf Assi, Abir Hussain, Hissam Tawfik
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages60-64
Number of pages5
ISBN (Electronic)9798350335149
DOIs
StatePublished - 2023
Event15th International Conference on Developments in eSystems Engineering, DeSE 2023 - Baghdad, Iraq
Duration: 9 Jan 2023 → 12 Jan 2023

Publication series

NameProceedings - International Conference on Developments in eSystems Engineering, DeSE
Volume2023-January
ISSN (Print)2161-1343

Conference

Conference15th International Conference on Developments in eSystems Engineering, DeSE 2023
Country/TerritoryIraq
CityBaghdad
Period9/01/23 → 12/01/23

Keywords

  • ADNI
  • Alzheimer's disease
  • Early Prediction
  • LOAD
  • Machine Learning

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