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Burden of diarrhea in the Eastern Mediterranean Region, 1990–2015: Findings from the Global Burden of Disease 2015 study

  • GBD 2015 Eastern Mediterranean Region Diarrhea Collaborators
  • University of Washington
  • American University of Beirut
  • Iran University of Medical Sciences
  • Imperial College London
  • Hunger Action Los Angeles
  • Mekelle University
  • GlaxoSmithKline
  • Weil Cornell School of Medicine
  • Lund University
  • Kermanshah University of Medical Sciences
  • Jimma University Ethiopia
  • University of Melbourne
  • University of Sydney
  • Mazandaran University of Medical Sciences
  • Joint Program of Family and Community Medicine
  • King Saud University
  • Universidad de Cartagena
  • Mansoura University
  • Institut de Recherche Clinique du Bénin (IRCB)
  • Laboratoire d'Etudes et de Recherche-Action en Santé (LERAS Afrique)
  • University of Management and Technology
  • Charles R. Drew University of Medicine and Science
  • University of California at Los Angeles
  • Jazan University
  • Universidade de São Paulo
  • Debre Berhan University
  • University of Venda
  • Haramaya University
  • Aga Khan University
  • University of Toronto
  • University of California at San Francisco
  • Al-Shifa Trust Eye Hospital
  • Walden University
  • University of Oxford
  • Wellcome Trust Research Laboratories Nairobi
  • Iranian Ministry of Health and Medical Education
  • Kirksville College of Osteopathic Medicine
  • International Institute for Population Sciences
  • Arba Minch University
  • Arak University of Medical Sciences
  • Karolinska Institutet
  • Bielefeld University
  • Saint James School of Medicine
  • Arabian Gulf University
  • Hamdan Bin Mohammed Smart University
  • Birzeit University
  • University of Colorado Denver
  • Heidelberg University 
  • Tehran University of Medical Sciences
  • Jordan University of Science and Technology
  • Health Services Academy
  • Ball State University
  • University of British Columbia
  • Parc Sanitari Sant Joan de Deu (CIBERSAM)
  • University of Montreal
  • London School of Hygiene and Tropical Medicine
  • Lahore College for Women University, Lahore
  • Liverpool University Hospitals NHS Foundation Trust
  • University of Liverpool
  • Aswan University
  • University West of Florida
  • Ministry of Health, Saudi Arabia
  • Alfaisal University
  • United Nations
  • Ahmadu Bello University
  • University of Nairobi
  • Western Sydney University
  • Alborz University of Medical Sciences
  • Contech International Health Consultants
  • Contech School of Public Health
  • Society for Health and Demographic Surveillance
  • Hampshire Hospitals NHS Foundation Trust
  • University College London Hospitals NHS Foundation Trust
  • Golestan University of Medical Sciences
  • Ain Shams University
  • Marshall University
  • Case Western Reserve University
  • University of KwaZulu-Natal
  • South African Medical Research Council
  • Independent Consultant
  • National Institute of Infectious Diseases
  • Sandia National Laboratories, New Mexico
  • International Medical University
  • University of California at Irvine
  • University of Virginia
  • King Fahad Medical City
  • Cleveland Clinic Foundation
  • Debre Markos University
  • Jagiellonian University Medical College
  • Wrocław Medical University
  • Federal Teaching Hospital
  • Norwegian Institute of Public Health
  • University of Bergen
  • Federal Institute for Population Research
  • Stellenbosch University
  • Ghent University
  • University of Saskatchewan
  • Shahid Beheshti University of Medical Sciences
  • Bahar Dar University
  • Kyoto University
  • Jackson State University
  • Public Health Foundation of India
  • Georgetown University
  • Independent Consultant

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children’s potential livelihood through growth faltering, cognitive impairment, and other sequelae. Methods: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)—the sum of years of life lost and years lived with disability—for both sexes and all ages. Results: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018–124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4–19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640–79,486). DALYs per 100,000 ranged from 304 (95% UI 228–400) in Kuwait to 38,900 (95% UI 25,900–54,300) in Somalia. Conclusions: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.

Original languageEnglish
Pages (from-to)109-121
Number of pages13
JournalInternational Journal of Public Health
Volume63
DOIs
StatePublished - 1 May 2018

Keywords

  • Burden of disease
  • Diarrheal diseases
  • Eastern Mediterranean Region

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