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Beyond Vision: Potential Role of AI-enabled Ocular Scans in the Prediction of Aging and Systemic Disorders

  • Moez Osama Omar
  • , Muhammad Jabran Abad Ali
  • , Soliman Elias Qabillie
  • , Ahmed Ibrahim Haji
  • , Mohammed Bilal Takriti
  • , Ahmed Hesham Atif
  • , Rangraze Imran
  • Ras Al Khaima Medical and Health Sciences University

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

In all medical subfields, including ophthalmology, the development of artificial intelligence (AI), particularly cutting-edge deep learning frameworks, has sparked a quiet revolution. The eyes and the rest of the body are anatomically related because of the unique microvascular and neuronal structures they possess. Therefore, ocular image-based AI technology may be a helpful substitute or extra screening method for systemic disorders, particularly in areas with limited resources. This paper provides an overview of existing AI applications for the prediction of systemic diseases from multimodal ocular pictures, including retinal diseases, neurological diseases, anemia, chronic kidney disease, autoimmune diseases, sleep disorders, cardiovascular diseases, and various others. It also covers the process of aging and its predictive biomarkers obtained from AI-based retinal scans. Finally, we also go through these applications existing problems and potential future paths.

Original languageEnglish
Pages (from-to)106-115
Number of pages10
JournalSiriraj Medical Journal
Volume76
Issue number2
DOIs
StatePublished - 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • AI-Driven ocular scans, Area under the curve (AUC)
  • Color Fundus Photography (CFP)
  • Convolutional Neural Network (CNN)
  • Machine Learning (ML)
  • ROPtool
  • deep learning
  • fundus autofluorescence
  • retinal age (RA)

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