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Association of the Red Cell Distribution Width with Complete Blood Count, Glycated Hemoglobin and Vitamin D in Patients with Type 2 Diabetes Mellitus- Across Sectional Study

  • Asaad Ma. Babker
  • , Rania Saad Suliman
  • , Nour A.M. Farajallah
  • , Fahad Al-Qahtani
  • , Dhafer Mubarak Alhadeb
  • , Qubaa Ahmed Elzubair
  • , Kiran S. Gopinath
  • , Anass M. Abbas
  • Prince Sultan Military College of Health Sciences - Al Dhahran
  • Gulf Medical University
  • King Fahd Military Medical Complex
  • Al Emadi Hospital
  • Al Jouf University

Research output: Contribution to journalArticlepeer-review

Abstract

The current study was aimed to assess the association of the Red Cell Distribution Width (RDW) with Glycated haemoglobin (HbA1C) and Vitamin D in Patients with Type 2 Diabetes Mellitus to provide insight into the potential physiological mechanisms and predictive significance of RDW fluctuations in patients with heart failure who are diabetic. Material &Methods: The cross-sectional design of this study was utilized to investigate a cohort of 150 patients who had received a diagnosis of type 2 diabetes mellitus. The assessment centered on the evaluation of comorbidities, red cell distribution width (RDW), and glycemic management in addition to vitamin D levels. Information was gathered via questionnaires, encompassing demographic details as well as medical history. Blood samples were assessed for RDW, total blood count, HbA1c, and Vitamin D concentrations using automated analyzers. The statistical analysis was performed utilizing version 27 of SPSS. Results: The study found low relationships between HbA1c and Vitamin D (r = -0.033, p = 0.691), RDW and HbA1c (r = -0.046, p = 0.573), and RDW and Vitamin D (r = -0.128, p = 0.118). Furthermore, Vitamin D had diverse connections with CBC values, suggesting a complex link within the setting of type 2 diabetes mellitus. Conclusion: The findings of the current study indicated an association between the RDW and RBCs, Hb and Red blood cell indices (HCT, MCV, MCH and MCHC) in patients with T2DM. The RDW could therefore serve as potential marker for the management of patients with T2DM.

Original languageEnglish
Pages (from-to)881-888
Number of pages8
JournalBiomedical and Pharmacology Journal
Volume17
Issue number2
DOIs
StatePublished - 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Glycated Hemoglobin
  • Red Cell Distribution Width
  • Vitamin D

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