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A Deep Learning Framework for the Prediction and Diagnosis of Ovarian Cancer in Pre- and Post-Menopausal Women

  • Blessed Ziyambe
  • , Abid Yahya
  • , Tawanda Mushiri
  • , Muhammad Usman Tariq
  • , Qaisar Abbas
  • , Muhammad Babar
  • , Mubarak Albathan
  • , Muhammad Asim
  • , Ayyaz Hussain
  • , Sohail Jabbar
  • Harare Polytechnic College
  • Botswana International University of Science and Technology
  • University of Zimbabwe
  • Al-Imam Muhammad Ibn Saud Islamic University
  • Prince Sultan University (PSU)
  • Quaid-I-Azam University

Research output: Contribution to journal › Article › peer-review

84 Scopus citations

Abstract

Ovarian cancer ranks as the fifth leading cause of cancer-related mortality in women. Late-stage diagnosis (stages III and IV) is a major challenge due to the often vague and inconsistent initial symptoms. Current diagnostic methods, such as biomarkers, biopsy, and imaging tests, face limitations, including subjectivity, inter-observer variability, and extended testing times. This study proposes a novel convolutional neural network (CNN) algorithm for predicting and diagnosing ovarian cancer, addressing these limitations. In this paper, CNN was trained on a histopathological image dataset, divided into training and validation subsets and augmented before training. The model achieved a remarkable accuracy of 94%, with 95.12% of cancerous cases correctly identified and 93.02% of healthy cells accurately classified. The significance of this study lies in overcoming the challenges associated with the human expert examination, such as higher misclassification rates, inter-observer variability, and extended analysis times. This study presents a more accurate, efficient, and reliable approach to predicting and diagnosing ovarian cancer. Future research should explore recent advances in this field to enhance the effectiveness of the proposed method further.

Original languageEnglish
Article number1703
JournalDiagnostics
Volume13
Issue number10
DOIs
StatePublished - May 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • augmentation
  • convolutional neural networks
  • diagnosis
  • epithelial ovarian cancer
  • histopathological images
  • prediction

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