Project Details
Description
In this study researchers want to gain more information on treatment patterns of patients treated with Xarelto in combination with acetylsalicylic acid (ASA). Both drugs reduce the risk of blood clots via different pathways. The study will enroll adult patients suffering from coronary artery disease (narrowing or blockage of vessels that supply the heart with blood) or peripheral artery disease (narrowing or blockage of vessels that supply the legs or head with blood). The study will focus on information on when and why physicians are starting to treat patients with Xarelto in addition to ASA, treatment duration, reasons to discontinue treatment and previous therapies. The study will also look into treatment outcomes for patients being treated with a combination of Xarelto and ASA by their physicians.
Layman's description
The study aims to collect real-world data on treatment patterns and decision points for treatment in patients with coronary artery disease (CAD) and/ or peripheral artery disease (PAD) treated with rivaroxaban 2.5 mg [twice daily] for the prevention of major cardiovascular events in adult patients with CAD at high risk of ischemic events and/ or documented PAD and to describe outcomes of an antithrombotic regime based on dual pathway inhibition (vascular dose of rivaroxaban 2.5 mg [twice daily] plus low-dose ASA [once daily]) across the broad range of patient risk profiles encountered in routine clinical practice.
| Acronym | XATOA |
|---|---|
| Status | Finished |
| Effective start/end date | 13/11/18 → 13/07/21 |
Collaborative partners
- Bayer AG (lead)
- Janssen, LP
- Departments of the Ministry of Health and Prevention
Keywords
- Coronary artery disease (CAD)
- Peripheral artery disease (PAD)
- Major adverse limb events (MALE)
- Major adverse cardiac events (MACE)
- Atherosclerosis
- Atherothrombosis
- Thrombosis
- Embolism
- Thromboembolism
- Arteriosclerosis
- Arterial Occlusive Diseases
- Vascular Diseases
- Cardiovascular Diseases
- Non-Steroidal Anti-Inflammatory Agents
- Non-Narcotic Analgesics
- Analgesics
- Sensory System Agents
- Peripheral Nervous System Agents
- Physiological Effects of Drugs
- Anti-Inflammatory Agents
- Antirheumatic Agents
- Fibrinolytic Agents
- Fibrin Modulating Agents
- Molecular Mechanisms of Pharmacological Action
- Platelet Aggregation Inhibitors
- Cyclooxygenase Inhibitors
- Enzyme Inhibitors
- Antipyretics
- Factor Xa Inhibitors
- Antithrombins
- Serine Proteinase Inhibitors
- Protease Inhibitors
- Anticoagulants
- Aspirin
- Rivaroxaban
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