Project Details
Description
This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease.
Layman's description
Eyes with loss of vision from retinal or optic nerve conditions generally considered irreversible will be treated with a combination of injections of autologous bone marrow derived stem cells isolated from the bone marrow using standard medical and surgical practices. Retinal conditions may include degenerative, ischemic or physical damage ( examples may include macular degeneration, hereditary retinal dystrophies such as retinitis pigmentosa, stargardt, non-perfusion retinopathies, post retinal detachment. Optic Nerve conditions may include degenerative, ischemic or physical damage ( examples may include optic nerve damage from glaucoma, compression, ischemic optic neuropathy, optic atrophy ). Injections may include retrobulbar, subtenon, intravitreal, intraocular, subretinal and intravenous. Patients will be followed for 12 months with serial comprehensive eye examinations including relevant imaging and diagnostic ophthalmic testing.
| Acronym | SCOTS2 |
|---|---|
| Status | Active |
| Effective start/end date | 1/01/16 → 31/07/26 |
Collaborative partners
- MD Stem Cells (lead)
- Medcare Orthopaedics & Spine Hospital
- Dubai Health Authority
Keywords
- Stem Cells
- Bone Marrow Derived Stem Cells
- BMSC
- Mesenchymal Stem Cells
- MSC
- Eye Disease
- Ophthalmology
- Ophthalmic Disease
- Retina
- Retinal Disease
- Macular Degeneration
- Age Related Macular Degeneration
- Myopic Macular Degeneration
- Geographic Atrophy
- Dry Macular Degeneration
- Wet Macular Degeneration
- Retinal Atrophy
- Retinal Dystrophy
- Hereditary Retinal Dystrophy
- Malattia Leventinese
- Retinitis Pigmentosa
- Stargardt Disease
- Cone Dystrophy
- Rod-Cone Dystrophy
- Cone-Rod Dystrophy
- Maculopathy
- Optic Nerve Disease
- Optic Atrophy
- Optic Neuropathy
- Ischemic Optic Neuropathy
- Optic Nerve Damage
- Optic Nerve Compression
- Compressive Optic Neuropathy
- Devics Syndrome
- Ushers Syndrome
- Neuromyelitis Optica
- Dominant Optic Atrophy
- Kjers Optic Atrophy
- Leber Hereditary Optic Neuropathy
- Blindness
- Vision Loss
- Retina Atrophy
- Eye Diseases
- Neuromuscular Diseases
- Retinal Degeneration
- Anatomical Pathological Conditions
- Hereditary Eye Diseases
- Retinal Dystrophies
- Inborn Genetic Diseases
- Cranial Nerve Diseases
- Vision Disorders
- Sensation Disorders
- Neurologic Manifestations
- Vascular Diseases
- Cardiovascular Diseases
- Hereditary Optic Atrophies
- Nervous System Heredodegenerative Disorders
- Neurodegenerative Diseases
- Mitochondrial Diseases
- Metabolic Diseases
- Peripheral Nervous System Diseases
- Optic Nerve Diseases
- Hereditary Leber Optic Atrophy
- Nervous System Diseases
- Low Vision
- Retinal Diseases
- Retinitis
- Atrophy
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.