Project Details
Description
This is a multicenter, randomized, double blind, parallel placebo controlled, phase 3 clinical trial to evaluate the protective efficacy, safety and immunogenicity of inactivated SARS-CoV-2 vaccines in healthy population 18 years old and above.
Layman's description
This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate the protective efficacy, safety and immunogenicity of inactivated SARS-CoV-2 vaccines in healthy population 18 years old and above. The participants were randomized into three groups of investigational vaccine 1, investigational vaccine 2 and placebo in a 1:1:1 ratio.2 doses of the investigational vaccine or placebo are inoculated into the deltoid muscle of the either arm according to the vaccination schedule of D0 & D21 (+7 days).According to the immune durability results in Phase I/II study, and cross-neutralization assay results, a third dose (booster dose) generates a better immune response and is estimated to offer better protection, therefore, a booster dose will be given after 3 months.
| Acronym | COVID-19 |
|---|---|
| Status | Finished |
| Effective start/end date | 16/07/20 → 31/12/21 |
Collaborative partners
- China National Biotec Group Company Limited (lead)
- G42 Healthcare
- Wuhan Institute of Biological Products Co., Ltd.
- Beijing Institute of Biological Products Co., Ltd.
- Abu Dhabi Health Services Company
- Al Qarain Primary Health Care Centre
- Emirates Health Services
Keywords
- SARS-CoV-2
- SARS-CoV-2 Vaccine
- Coronavirus
- Immunologic Factors
- Physiological Effects of Drugs
- Vaccines
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