Personal profile
Research interests
- Retinal stimulation using multielectrode arrays as implantable devices for restoration of vision in retinal degeneration (collaborative work with Colleagues in South Korea – Chungbuk National University, Cheongju).
- Human physiological studies of alertness and the effects of different interventions (e.g. sleep deprivation) on alertness and autonomic modulation. Human biopotentials being recorded and analyzed for this purpose include: ECG and beat-to-beat blood pressure (for autonomic modulation), EEG and evoked potentials in combination with cognitive function testing for assessment of levels of alertness. Additionally, we measure blood flow to the prefrontal cortex using a functional near infrared imaging (fNIR) method, as an indicator of prefrontal cortical function during the performance of cognitive tasks.
- Mechanosensory transduction in cutaneous receptors - I have continued to have an enduring interest in the area of somatosensory transduction – the conversion of environmental or endogenous stimuli into transmissible action potentials by sensory neurons. Recently we have focused on the effect of glutamate receptor antagonists on somatosensory transduction. We have continued to use our robust isolated preparation to study the sensory receptors in the vibrissal follicles. Our focus is shifting to understanding how potassium channels modulate the mechanosensory activity in the touch receptors.
- Pain mechanisms and acupuncture antinociception - My research interest is in pain mechanisms and unconventional interventions is partly informed by my interest and training in Traditional Chinese Medicine.
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